The Regional Institute will mark its 10th anniversary by reflecting on the issue of change - how it happens, why we resist it and what it means for the Buffalo Niagara region - at a symposium to be held Oct. 11. The Symposium on Change, which will convene regional leaders, community activists and the general public, will be held in Asbury Hall in The Church, 341 Delaware Ave., Buffalo, from 12:30-5 p.m., with a reception to follow.